Plague's End/Quick guide

Starting out

 * Talk to Arianwyn in Lletya. (Chat options 1-Accept Quest-1-1)
 * Enter western door

Infiltration

 * Open northern door (Chat options 3-2-1)
 * Head to the north-western room.
 * Talk to Mourner
 * Talk to Iestin Edern (Chat options 2)

Iorwerth's master plan

 * Climb up northern stairs
 * Talk to Mayor of Prifddinas (In the house north of the camp) (Chat options 2)
 * Talk to the Mourner at the bridge (South-west side of the camp) (Chat options 1)
 * Return to Mayor of Prifddinas (In the house north of the camp) (Chat options 1)
 * Take Iorwerth masterplan (desk option)
 * Return to Iestin Edern (Chat options 1-3)

Incite an uprising

 * Talk to Councillor Halgrive (outside of East Ardougne church) (Chat option 1)
 * Talk to Bravek (in the upper floor of West Ardougne Civic Office) (Chat option 1-2-2)
 * Talk to the 6 people on the list (take off 1 Mourner piece, or they won't speak with you)
 * Ted or Martha Rehnison - In a building north of the civic office (Chat option 1)
 * Jethick - East side of the town square (Chat option 1)
 * Nurse Sarah - In a building south-west of the church (Chat option 1)
 * Carla - In an open area, north of the graveyard to the west of the church (Chat option 1)
 * Koftik - Entrance to the Underground Pass. (Chat option 1)
 * Elena - Found in the house just west of the log balance in the northern part of East Ardougne. (Chat option 1)

Time to attack
Prepare for some combat.
 * Return to the church in West Ardougne
 * Talk to any of the 6 NPCs at the church (not the priest) (Chat options 1-5)
 * Head to the Mourners HQ (north-east)
 * Kick down door and kill the mourners
 * Open trapdoor in north-west corner and kill the mourners, including Head Mourner
 * Talk to Head Mourner (Chat options 1-2-3-2)
 * Head to the roof, replace Standard (hold spacebar)
 * Head to King Lathas's Castle
 * Talk to Sir Edmond near the entrance to begin (Chat options 1)
 * Head upstairs, talk to King Lathas
 * Kill Sir Hugo (Chat options 1-2)
 * Kill or spare Lathas, then talk to Sir Edmond
 * Return to Iestin Edern (Chat options 3-2-1)
 * Search bookcase (in the northern room) for The Lost Elders (Chat option 1)
 * Read The Lost Elders book
 * Talk to Gwir for 2 items(Chat options 1-4-5-2)

Finding Lady Ithell
All Symbols are on the walls, but near the floor.
 * Inspect Symbol (ranging shop, west wall)
 * Inspect Symbol (southern building, south wall)
 * Inspect Symbol (bank, east wall)
 * Climb upstairs (Centre of Lletya)
 * Inspect Symbol (northern wall of Altar room, but outside)
 * Climb downstairs (Centre of Lletya)
 * Enter clothing store (north-west building with Oronwen) and climb stairs.
 * Inspect Symbol (south-western corner of the small room)
 * Head to the centre of Lletya
 * Build Statue Hotspot (directly next to the well in the centre).
 * Climb upstairs
 * Speak to Kelyn (Chat option 4)

Finding Lady Trahaeam

 * Head west, out of Lletya.
 * Pass Tree. (west)
 * Step over trip-wire. (west)
 * Enter dense forest x3 (north-west)
 * Jump Leaves. (north-east)
 * Enter Cave Entrance (far east, near summoning obelisk)
 * Head East, Mine Cracked Wall (south of the Well)
 * Enter Tunnel
 * Kill level 70 Automaton(x3)
 * Wake Trahaearn, (Chat options 1-3)

Finding Lord Crwys

 * Home teleport to Tirannwn Lodestone
 * Pick (blue) Mushroom (they are very bright)
 * Enter Dense Forest x3 (west of Tirannwn Lodestone)
 * Pick (red) mushroom (these are for later)
 * Step over trip-wire (north-west)
 * Enter dense forest x2 (north - do not pass the third one)
 * Chop down tree (east)
 * Inspect tree (west)
 * Use Plant Cure on Tree
 * Talk to Lord Crwys (Chat option 4)

Finding Lady Hefin

 * Home teleport to Tirannwn Lodestone
 * Jump Leaves (north-east)
 * Step over trip-wire (north-east)
 * Head far south to the swamp, past the magic trees.
 * Jump to rocks (look at the map on the right)
 * Talk to Elf Hermit (Chat options 2-2-1-3-4)

Finding Lord Amlodd

 * Home teleport to Taverley, head East across the pond to the summoning obelisk.
 * Infuse-pouch Obelisk (Chat option 1-1)
 * Summon Amlodd pouch (Chat option 4)

Finding Lady Meilyr

 * Grind Blue Isafdar Mushroom
 * Grind Red Isafdar Mushroom
 * Use on super defence (3) potion.
 * Teleport to Daemonheim (Ring of Kinship)
 * Drink Meilyr's Potion in the entrance area to the dungeons.
 * Enter Portal (West side)
 * Speak to Lady Meilyr (Chat option 4)

Distraction

 * Speak with Iestin Edern (Chat option 3)
 * Travel to Tyras Camp (West of Tirannwn Lodestone) (or charter ship to Tyras Camp via Port Sarim)
 * Speak with General Hining (Chat option 4)
 * Return and speak with Iestin Edern (Prepare for combat - Fire Magic Weakness)

Boss fight
Puzzles Tip: It is best to work in reverse with the mirrors' beam (predicting the beam of light from the Seren seal) up until the locked mirrors (phase 4+).
 * Enter Grand Library (Spacebar - 2)
 * Direct Light into the centre (place/rotate mirrors as needed)
 * Use Protect/Deflect Magic and keep moving when Dark Lord is alive
 * Talk to Arianwyn
 * Quest complete!