Supreme overload potion

The supreme overload potion is a six-dose combination potion that can be made at level 98 Herblore after buying the recipe for 900,000 coins from Lady Meilyr (you do not need to find this recipe in Daemonheim). It is made by combining an overload (4) with super attack (4), super defence (4), super strength (4), super ranging potion (4) and super magic potion (4), in a crystal flask. This gives 600 experience.

A dose of supreme overload is a slightly better version of regular overload -- it boosts the five combat skills by 16% + 4, rather than 15% + 3. Assuming level 99 in the relevant skills, this is a boost of +2 over a regular Overload. Each dose lasts 6 minutes, for a total of 36 minutes per flask.

A supreme overload (6) is one of the ingredients used to create a Supreme overload salve.

Trivia

 * The supreme overload potion gives the largest visible stat boost for any skill.